Embedded Files
2025
2025
Siyi Wang, Joanna R Kovalski, Francisco J Zapatero-Belinchón, Maxwell Bennett, Duygu Kuzuoglu-Öztürk, Qiongyu Li, Erica Stevenson, Jie Liu, Nevan J Krogan, Melanie Ott, Danielle L Swaney, Davide Ruggero, Kevin Lou, Kevan M Shokat. Programmable translational inhibition by a molecular glue-oligonucleotide conjugate. Biorxiv (2025).
Kovalski JR, Sarioglu G, Subramanyam V, Hernandez G, Rademaker G, Oses-Prieto JA, Slota M, Mohan N, Yiakis K, Liu I, Wen KW, Kim GE, Miglani S, Burlingame AL, Goodarzi H, Perera RM, and Ruggero D. Functional screen identifies RBM42 as a mediator of oncogenic mRNA translation specificity. Nature Cell Biology (2025).
2023
2023
Macaya I, Roman M, Welch C, Entrialgo-Cadierno R, Salmon M, Santos A, Feliu I, Kovalski J, Lopez I, Rodriguez-Remirez M, Palomino-Echeverria S, Lonfgren SM, Ferrero M, Calabuig S, Ludwig IA, Lara- Astiaso D, Jantus-Lewintre E, Guruceaga E, Narayanan S, Ponz-Sarvise M, Pineda-Lucena A, Lecanda F, Ruggero D, Khatri P, Santamaria E, Fernandez-Irigoyen J, Ferrer I, Paz-Ares L, Drosten M, Barbacid M, Gil-Bazo I, Vicent S. Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer. Nature Communications (2023).
2022
2022
Kovalski JR*, Kuzuoglu-Ozturk D*, Ruggero D. Protein synthesis control in cancer: selectivity and therapeutic targeting. EMBO Journal (2022). Review.
2021
2021
Kovalski JR*, Xu Y*, Ruggero D. Examining Myc-Dependent Translation Changes in Cellular Homeostasis and Cancer. Methods in Molecular Biology: The Myc Gene (2021). Book chapter.
2019
2019
Che Y, Siprashvili Z, Kovalski JR, Jiang T, Wozniak G, Elcavage L, Khavari PA. KRAS regulation by small non-coding RNAs and SNARE proteins. Nature Communications (2019).
Kovalski JR, Shanderson RL, Khavari PA. Ras functional proximity proteomics establishes mTORC2 as new direct ras effector. Oncotarget (2019).
Kovalski JR, Bhaduri A, Zehnder AM, Neela PH, Che YC, Wozniak GG, Khavari PA. The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2. Molecular Cell (2019). Feature Resource article.
2018
2018
Ramanathan M, Majzoub K, Rao DS, Neela PH, Zarnegar BJ, Mondal S, Roth JG, Gai H, Kovalski JR, Siprashvili Z, Palmer TD, Carette JE, Khavari PA. RNA-protein interaction detection in living cells. Nature Methods (2018).
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