A postdoctoral research fellow position is available in the newly established Kovalski lab at the University of North Carolina at Chapel Hill to study the molecular mechanisms of post-transcriptional gene expression in health and disease. We are an enthusiastic, collaborative team dedicated to tackling outstanding questions at the interface of RNA biology and cancer biology. Several open questions in the lab include: how do RNA binding proteins remodel the cellular proteome to drive oncogenic transformation? How are RBPs functionally repurposed as cells transition from a healthy to malignant state? How do RNA binding proteins coordinate selective translation of key oncogenes to enable cancer cells to rapidly adapt to stress and therapy?
The potential candidate will utilize cell culture models and proximity proteomics to map RBP interaction networks across cellular compartments, in combination with CLIP-sequencing, RNA structure probing, polysome-sequencing, and in vivo cancer mouse models to dissect mechanisms of post-transcriptional control in normal and cancer cells.
Apply online here: https://unc.peopleadmin.com/postings/318679.
Posted by Joanna Kovalski 5/14/26
The Kovalski lab welcomes Caitlin Birthright, a PhD student in Chemical Biology and Medicinal Chemistry at the UNC Eshelman School of Pharmacy. She's excited to explore the role of RNA structure in driving oncogenic translation programs.
Posted by Joanna Kovalski 3/10/26
The Kovalski lab officially opened on January 12, 2026! We are part of the Department of Biochemistry and Biophysics as well as the Lineberger Comprehensive Cancer Center.
You can read more here.
Posted by Joanna Kovalski 1/27/26